Biomolecular Probes

NucleoSyn provides several kinds of biomolecular probes:

Chemical tools/probes for target validation:

Proof that modulation of the identified target in a model system has the desired impact on biological activity and can be linked to therapeutic utility is essential to minimize phase II clinical trial failures due to lack of efficacy (see the following reference: Target validation using chemical probes – Nature Chemical Biology 9,195–199 (2013) doi:10.1038/nchembio.1197). NucleoSyn provides specific and well characterized chemical tools/probes to support your target validation research.

Reference bioactive compounds:

NucleoSyn provides reference bioactive chemicals that may be used as a benchmarking tool for your own product (e.g. drug candidates or active cosmetic ingredients developed by competitors that are not commercially available).

Molecular labeled compounds for chemical biology applications:

NucleoSyn provides custom molecular labeled compounds for chemical biology applications. Examples of molecular labels include the following:

• Biotin label
• Stable Isotope labels (²H, ¹³C, ¹⁵N)
• Fluorophore labels (e.g. Lissamine Rhodamine B)
• Crosslinking and Photoaffinity labels
• Site directed spin labels – SDSl (use in EPR: electron paramagnetic resonance (EPR) spectroscopy)

Please do not hesitate to contact us using our contact form for your specific needs in term of biomolecular probes.

Please note that products offered by NucleoSyn are for R&D use only.

A list of common Biomolecular Probes will be coming soon.